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TG Therapeutics Stock (TGTX) Great Growth and Fair Valued (Q4 2024 Earnings)

​TG Therapeutics, Inc. (NASDAQ: TGTX) has emerged as a notable player in the biotechnology sector, demonstrating remarkable growth and presenting a compelling investment opportunity. TGTX stock has been up 58% since my report on 6 November 2024. The company's robust financial performance, innovative product pipeline, and strategic market positioning have contributed to its impressive stock appreciation. In this blog post, we will delve into TG Therapeutics' corporate overview, financial achievements, stock performance, valuation metrics, growth prospects, and potential risks to provide a comprehensive analysis for investors.​

Biotech

About TG Therapeutics

Founded in 1993 and headquartered in Morrisville, North Carolina, TG Therapeutics is a commercial-stage biopharmaceutical company specializing in the development and commercialization of novel treatments for B-cell diseases. The company's primary focus is on BRIUMVI® (ublituximab-xiiy), an anti-CD20 monoclonal antibody approved for treating adult patients with relapsing forms of multiple sclerosis (RMS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. Beyond BRIUMVI, TG Therapeutics is advancing a pipeline of investigational medicines targeting various B-cell malignancies and autoimmune diseases, underscoring its commitment to addressing unmet medical needs in these domains.

Read More: NVIDIA Stock (NVDA) Strong Growth and Good Value (Q4 2025 Earnings)

TG Therapeutics Financial Performance

TG Therapeutics has reported robust financial results, reflecting its successful commercialization strategies and strong market adoption of its therapies. In Q4 2024, the company generated revenue of $108.19 million, marking a substantial 146.04% increase from $43.97 million in Q4 2023. On a trailing twelve months (TTM) basis, revenue grew by 40.8%, reaching $329 million compared to $233.66 million in the prior year. The company also demonstrated significant earnings growth, with EPS improving from a loss of $0.10 per share in Q4 2023 to a positive $0.15 in Q4 2024. On a TTM basis, EPS increased by 68.04%, rising from $0.09 in Q4 2023 to $0.15 in Q4 2024. Looking ahead, analysts project continued strong growth, forecasting revenue of $571.55 million for 2025, a 73.72% increase from 2024, while EPS is expected to surge by 493.86% to $0.89, highlighting the company’s potential for further financial expansion.

TGTX Stock Price Performance and Valuation

TG Therapeutics (TGTX) has exhibited exceptional stock price growth over the past year, significantly outperforming the broader market. As of its most recent trading price of $43 per share, the stock has surged by an impressive 181.9% in the past year, vastly exceeding the 8% increase seen in the S&P 500 over the same period. This substantial growth underscores strong investor confidence in the company’s financial performance, product adoption, and future earnings potential.

TGTX Stock vs S&P 500 March 2024-2025

Despite this remarkable price appreciation, TGTX remains fairly valued when considering its growth trajectory and industry benchmarks. The company's price-to-sales (P/S) ratio on a trailing twelve-month (TTM) basis stands at 18.99, reflecting investor optimism about its revenue expansion. However, the forward P/S ratio is significantly lower at 10.42, indicating that anticipated revenue growth could make the stock more attractive over time. Similarly, while the current price-to-earnings (P/E) ratio is high at 286.6, reflecting early-stage profitability, the forward P/E ratio of 40.45 suggests that future earnings growth will bring the valuation down to more reasonable levels.

Given the company's strong revenue growth, expanding market presence, and improving profitability, TGTX remains an appealing investment opportunity. The decline in forward valuation ratios signals that the company is expected to generate significant earnings growth in the near future, making the stock attractive despite its recent run-up. Investors with a long-term growth perspective could still find TGTX to be a compelling investment within the biotech sector.

TG Therapeutics Growth Potential

Several factors contribute to TG Therapeutics' promising growth outlook:​

  • Product Portfolio: The successful commercialization of BRIUMVI has been a significant revenue driver. In Q4 2024, BRIUMVI generated $103.6 million, contributing to annual sales of $310 million, marking a 250% year-over-year increase. The company projects BRIUMVI sales to reach $540 million in 2025, indicating strong market adoption and growth potential.
  • Pipeline Development: TG Therapeutics is actively developing additional therapies targeting B-cell diseases, which could diversify its revenue streams and enhance its market position.
  • Market Dynamics: The global multiple sclerosis treatment market is expected to grow, providing a favorable environment for the company's flagship product, BRIUMVI.​

Risks to Consider

While TG Therapeutics presents a compelling investment case, potential investors should be mindful of the following risks:

  • Competition: BRIUMVI faces competition from established treatments like Roche's Ocrevus and Novartis' Kesimpta. The company's ability to differentiate its product and capture market share is crucial.
  • Regulatory Environment: The biopharmaceutical industry is subject to stringent regulatory standards. Any changes in regulations or delays in product approvals could impact the company's operations.​
  • Market Volatility: Biotech stocks are often subject to higher volatility due to factors like clinical trial outcomes, product performance and market sentiment​.

Conclusion

TG Therapeutics has demonstrated exceptional growth through its innovative therapies and strategic market positioning. The company's strong financial performance, coupled with a promising product pipeline and favorable market dynamics, underscores its potential as a valuable addition to an investment portfolio. While acknowledging inherent risks, the company's achievements and future prospects present a compelling case for investors seeking exposure to the biotechnology sector.

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